Angleški jezik Naslov: The efficacy and safety of ramipril as monotherapy and in fixed-dose combination with hydrochlorothiazide in the treatment of different groups of hypertensive patients and its effect on cardiovascular kardio hipertenzija Izvleček: Hypertension is a major health problem in the world.
One in every three adultshas high blood pressure BP. The excessive pressure on the artery wallscaused by high BP can damage blood vessels, as well as organs in the body.
Uncontrolled high BP can lead to different complications. Hypertension is accompanied by cardiovascular risk factors, such as diabetes, previous myocardial infarction or stroke, dyslipidemia, obesity or proven vascular disease, in at least twothirds of all cases. Todayʼs treatment of hypertensionis very challenging, especially in patients with enhanced cardiovascular risk, where a multiple pharmacological approach is often required to achieve an acceptable BP goal.
Ramipril is a lipophilic ACE inhibitor suitable for once-daily administration. It effectively reduces peripheral vascular resistance, thus regulating high BP. In kardio hipertenzija with hydrochlorothiazide, it produces a synergetic effect, which increases the efficacy and safety of both drugs.
Ramipril has been studied in numerous clinical studies.
Also the efficacy and safety of Krkaʼs ramipril AmprilŽ have been studied in several clinical and post-authorisation safety and efficacy studies. Krkaʼs ramipril is offered in a variety of dosage forms, strengths and fixed-dose combinations.
Podobna dela Podobna dela v drugih slovenskih zbirkah: Komentarji Za komentiranje se morate prijaviti.
Hipertenzija Hipertenzija ili povišen krvni tlak je akutno ili kronično stanje povišenog arterijskog pritiska. WHO također naglašava da je povišeni krvni tlak stanje i bolest koje je podložno ogromnom utjecaju i promjenama uslijed pridržavanja zdravog načina prehrane i redovitog vježbanja.